Erik, Ryan, and Cooze start college and pledge the Beta House fraternity, presided over by none other than legendary Dwight Stifler. But chaos ensues when a fraternity of geeks threatens to stop the debauchery and the Betas have to make a stand for their right to party.

Maltazard, the Evil M, is now 7 feet tall and evolving among the humans, causing terror wherever he goes. His goal is simple: forming an army of giant henchmen and ruling over the universe. Meanwhile, Arthur is still a Minimoy, and thus in a state where he’s unable to fend him off. With the help of Selenia and Betameche, he hatches a plan to regain his usual size: all they must do is infiltrate Arthur’s house through the pipeworks, catch an electric train from his bedroom to his grandfather’s study and find an elixir that will make him grow back to his human size. Sounds simple enough, if it weren’t for Darkos, Maltazard’s own son, hot on their tails.

At Adams College, the jocks rule the school from their house on high, the Alpha Beta fraternity. So when a group of socially-challenged misfits try to go Greek, they’re instantly rejected by every house on campus. Deciding to start their own fraternity to protect their outcast brothers, the campus nerds soon find themselves in a battle royale as the Alpha Betas try to crush their new rivals.

Christine (Jennifer Holland) and Reagan (Kate Plec) are a pair of young women who get to know each other when they end up sharing a dorm room in college. Christine is a studious type who is still getting over a family tragedy, while Reagan never lets her classes get in the way of a good time. Convinced Christine needs to get out more, Reagan persuades her to tag along as she attends a wild party at the Beta Alpha Tau sorority house. Both Christine and Reagan are impressed with the BAT house, and in particular, chapter president Devin (Michelle Borth), and they are soon invited to join. However, Ms. Masters (Barbara Crampton), who teaches a class on the paranormal, believes that the BAT house is the center of supernatural activity on campus, and urges Christine to inform her of the goings-on at the house. It isn’t long before Christine finds out that Ms. Masters’ fears were based in fact, but can she tear herself away from the decadent pleasures sorority life has brought to her?